This Test Could Find Arthritis Before Your Joints Hurt

This Test Could Find Arthritis Before Your Joints Hurt

Patients could soon be diagnosed with early-stage arthritis several years before the onset of physical and irreversible symptoms, scientists say.

Researchers developed a test that can provide an early diagnosis of osteoarthritis (OA) and also distinguish it from early-stage rheumatoid arthritis (RA) and other self-resolving inflammatory joint disease.

The test, which could be available to patients within two years, identifies the chemical signatures found in the plasma of blood joint proteins damaged by oxidation, nitration, and glycation; the modification of proteins with oxygen, nitrogen, and sugar molecules.

Diagnosing which type of arthritis a patient will develop at an early-stage will allow for appropriate treatment that will provide the best chance for effective treatment and potential prevention.

For the study, published in the journal Arthritis Research and Therapy, plasma and synovial fluid samples were taken from patients with early-stage and advanced OA, RA, or other inflammatory joint disease and from a control group of those with good skeletal health.

The findings showed damaged proteins in characteristic patterns in the samples of those patients with early and advanced OA and RA, but at markedly lower levels in the samples of those in the control group—providing identifiable biomarkers necessary for early detection and diagnosis.

“Damage to proteins in the arthritic joint have been known for many years but this is the first time it has been exploited for early-stage diagnosis,” says Naila Rabbani of Warwick Medical School.

“For the first time we measured small fragments from damaged proteins that leak from the joint into blood. The combination of changes in oxidized, nitrated, and sugar-modified amino acids in blood enabled early stage detection and classification of arthritis—osteoarthritis, rheumatoid arthritis, or other self-resolving inflammatory joint disease.

“This is a big step forward for early-stage detection of arthritis that will help start treatment early and prevent painful and debilitating disease.”

Source: University of Warwick

Related Books:

at InnerSelf Market and Amazon

 

More Articles By This Author

You May Also Like

follow InnerSelf on

facebook icontwitter iconyoutube iconinstagram iconpintrest iconrss icon

 Get The Latest By Email

Weekly Magazine Daily Inspiration

AVAILABLE LANGUAGES

enafarzh-CNzh-TWdanltlfifrdeeliwhihuiditjakomsnofaplptroruesswsvthtrukurvi

MOST READ

baby smiling
Renaming and Reclaiming the Sacred
by Phyllida Anam-Áire
Walking in nature, eating delicious food, poetry, playing with our children, dancing and singing,…
An Equinox Altar
Making An Equinox Altar and Other Fall Equinox Projects
by Ellen Evert Hopman
Fall Equinox is the time when the seas become rough as the winter gales set in. It is also the…
curous kids 9 17
5 Ways To Keep Kids Curious
by Perry Zurn
Kids are naturally curious. But various forces in the environment can dampen their curiosity over…
digital money 9 15
How Digital Money Has Changed How We Live
by Daromir Rudnyckyj
In simple terms, digital money can be defined as a form of currency that uses computer networks to…
Like Genes, Your Gut Microbes Pass From One Generation To The Next
Like Genes, Your Gut Microbes Pass from One Generation to the Next
by Taichi A. Suzuki and Ruth Ley
When the first humans moved out of Africa, they carried their gut microbes with them. Turns out,…
renewable power 9 15
Why It’s Not Anti-Environmental To Be In Favour Of Economic Growth
by Eoin McLaughlin etal
In the midst of today’s cost of living crisis, many people who are critical of the idea of economic…
quiet quitting 9 16
Why You Should Talk To Your Boss Before 'Quiet Quitting'
by Cary Cooper
Quiet quitting is a catchy name, popularised on social media, for something we’ve all probably…
hiding inflation 9 14
3 Ways Companies Change Their Products To Hide Inflation
by Adrian Palmer
There are certain product changes that businesses can and do make to try to quietly fold increased…

New Attitudes - New Possibilities

InnerSelf.comClimateImpactNews.com | InnerPower.net
MightyNatural.com | WholisticPolitics.com | InnerSelf Market
Copyright ©1985 - 2021 InnerSelf Publications. All Rights Reserved.